Is Microsatellite instability (MSI) testing right for you?
If you have been diagnosed with colorectal or endometrial cancer with abnormal MSI and/or Immunohistochemistry (IHC) results, this test can help you make key decisions about your treatment.
Microsatellite instability (MSI) means your genes are more likely to have a mutation – it’s something which can happen when your DNA does not repair itself in the normal way, so-called DNA mismatch repair deficiency (MMRd).
This test analyses colon, endometrial, and other tumour tissue samples to screen for MMRd and to find out if you are at risk for Lynch syndrome (a particular type of colorectal cancer).
Ask your clinician how you can get this test – and about our other tests which look at aspects of colorectal cancer to find out which one is right for you.
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Would PD-L1/PD-1 immunotherapy drugs help me?
PD-LI or PD-1 immunotherapy is a treatment which effectively harnesses the power of your body’s own immune system to treat your cancer – and this test can show if you would be likely to benefit from it.
It can also show if you are at risk for Lynch syndrome and generally help you and your clinician decide on any treatments most likely to help you.
You can discuss this with your clinician, or if you would like to talk to one of our experts about the test, call us on +44 (0) 7495 981816.
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What do I have to do?
This test is an analysis of your tumour tissue. You will have had a biopsy before you received your cancer diagnosis, and may be able to use the sample taken at that time so you do not need an additional medical procedure to take this test.
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What do I have to do?
This test is only available with authorisation from your clinician, who will receive your test results directly.
Step 1. Purchase and permission
Buy the test. You will receive an email asking you to confirm that you have authorised ELG to be given a sample of your tumour tissue.
Step 2. Collection of sample
We will contact your clinician directly and organise the collection of your sample and delivery to the laboratory.
Step 3: Analysis and reporting
Your sample will be analysed and a report will be generated, usually within three to four weeks of receipt of your sample in the lbaoratory.
Step 4: Results
Your clinician will receive the test report and will then be able to talk to you about the next steps to help you get the most effective treatment or further screening.
This test is provided by:
